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PCA was used to identify major patterns of gene expression [ 79].
We previously observed that EEDS treatment induced two major patterns of gene expression in A549 human lung cancer cells [ 6].
We were able to identify three major patterns of gene expression and over-represented gene ontology categories during stem development.
gambiae mosquito abdomen-derived cDNA libraries to elucidate major patterns of gene expression through 48 hours post ingestion of a blood meal.
Differentially expressed genes between stages of leaf or cotyledon development were determined, major patterns of gene expression were defined, and shared genes were identified.
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This is somehow surprising since it was suggested that the shared NFкB driven gene expression changes mediated by LPS, CD40L, αIgM or BAFF would be dominant in defining the major pattern of gene expression changes.
In order to achieve global gene expression changes to describe major pattern of gene expression and to identify pathway activity in aggressive NHL we used as our model system, the BL2 cell line, which is derived from germinal centre B cells [ 33- 35].
To obtain more clues about the major patterns of temporal gene expression over 12 months, we performed a K-mean cluster analysis to identify distinct clusters (Figure 3; Dataset S2).
This global analysis of the microarray shows four major patterns of coordinated gene expression.
This study showed that the early stages of allohexaploidization, leading to the formation of allohexaploid wheat, exhibited two major patterns of global gene expression alteration: parental dominance expression and non-additive expression.
Comparison with the parental plants coupled with inclusion of empirical mid-parent values (MPVs) revealed that whereas the great majority of genes showed the expected parental additivity, two major patterns of alteration in gene expression in the allohexaploid lines were identified: parental dominance expression and non-additive expression.
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