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In living cells, the endocytosis involves three major pathways, including caveolae-mediated endocytosis, macropinocytosis, and clathrin-mediated endocytosis.
There are several major pathways including non-homologous end joining (NHEJ), nucleotide and base excision repair (NER and BER), mismatch repair (MMR) and somatic homologous recombination (SHR) [for reviews see e.g. 3], [4], [5].
TPO stimulation activates three major pathways including JAK/STATs, MAPK/ERK, and PI3K/AKT, which promote cell proliferation and eventually drives progenitor cells to commit into megakaryocyte lineage.
Proteins in the cross-talk analysis are classified into three major pathways, including TNFα, IL-1, TLR-4 (for both MyD88-dependent and MyD88-independent) pathways.
Proteins in this cross-talk analysis were classified into four major pathways, including TNFα, IL-1, MyD88-dependent and MyD88-independent pathways.
These differential proteins are involved in physiological, metabolic, and cellular processes, with major pathways including "cysteine metabolism", "valine, leucine and isoleucine degradation", and "MAPK signaling".
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Based on the observed product distribution, two major reaction pathways, including dehydrogenation, amination and hydrogenation of polyols, ammoniation and ring opening of piperazines, are proposed.
In vitro effects of p38 inhibitors (p38i) on cytokine regulation were compared to inhibitors of other major signalling pathways including PI3 kinase, JNK, MEK-1, NF-κB or protein kinase C (PKC).
The lab has helped to define major signaling pathways, including Ras/ERK/RSK and PI3K/Akt and has performed extensive analyses of mTOR, a checkpoint kinase that deftly integrates signals emanating from growth factors and environmental conditions to guide cellular decisions.
In addition, it is becoming clear that SA interacts both negatively and positively with other major signaling pathways, including those regulated by jasmonic acid and ethylene (Raskin 1992).
Selenium is an essential element for antioxidant reactions in humans and animals and an important component of several major metabolic pathways, including synthesis of thyroid hormone metabolism, antioxidant defense systems and immune functions (Kohrle and Gartner 2009; Gandhi et al. 2013).
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