Sentence examples for major pathway regulating from inspiring English sources

We examined the expression of genes regulating the metabolism of very low density lipoprotein (VLDL), a major pathway regulating hepatic triglyceride export; Apoa4 was highly up-regulated in ob/ob mice but its expression was not affected by TUDCA treatment.

The second major pathway regulated in response to WOA treatment was a significant down-regulation of RNA synthesis and ribosome biogenesis genes, which was mostly apparent upon chronic exposure.

Comparative expression analysis revealed wound healing as a major pathway regulated by both ATM and mutant p53.

Two major pathways regulating the immune response are the JAK/STAT and MAPK/ERK pathways.

The major pathways regulating PDAC-associated inflammation are now being explored.

Although the GH/IGF1axis is one of the major pathways regulating aging in mammals, its precise downstream mechanisms remain a subject of debate and scrutiny.

The functional consequences of NAD+(H) depletion upon FK866 treatment resulted in a marked inhibition of the three major pathways regulating the translation process and in a striking arrest of protein synthesis.

This provides strong pharmacological evidence that p110α is the most important isoform in the pathways acutely regulating glucose metabolism, and that functional redundancy between PI3K isoforms is unlikely to be a major feature of major pathways regulating glucose metabolism in vivo [ 32].

Indeed, by the two cell stage, the major pathways regulated by maternal mRNA are targeted protein degradation, translational control and chromatin remodelling [ 2].

Indeed, the major pathways regulated by EGC in IEC identified with microarrays lead to enhanced cell adhesion, differentiation, and motility, which could favor repair, and reduced cell proliferation.

The BMP pathway is the major signaling pathway regulating Drosophila GSC self-renewal as well as proliferation (Song et al. 2004; Li and Xie 2005).