Sentence examples for major pathological effects from inspiring English sources

Instead small and soluble Aβ oligomers are suggested to exert the major pathological effects.

Its major pathological effects are on the nervous and reproductive systems and the developing embryo/fetus.

In sum, our study charts how a single anchored PKA phosphorylation event that subtly changes the conformation of a key lens membrane protein can be magnified leading to major pathological effects at the cellular and tissue levels.

Infection of amphibians by the chytridiomycete fungus Batrachochytrium dendrobatidis (Bd) is currently responsible for a major pandemic whose lethal pathological effects are implicated in widespread extinctions of susceptible host populations.

Protein aggregation and its pathological effects are the major cause of several neurodegenerative diseases.

25 High glucose concentration, a major pathological characteristic of diabetes, may have toxic effects on neurons in the brain through several mechanisms.

Since bone erosions are also a major pathological feature of RA, we examined the effects of these cytokine combinations on bone in this model.

To evaluate the possible cell type specificity of the carcinogenic effect of SO2 from air pollutants on lungs, two major pathological types (AC and squamous cell carcinoma [SCC]) in Taiwan were considered.

ROS constitute a major pathological factor causing many serious diseases, including cancer and neurodegenerative disorders [32].

Only < 10% tumor cells were viable in all resected specimens, indicating major pathological response to alectinib.

The death of dopaminergic neurons is a major pathological hallmark of Parkinson's disease (PD).