Sentence examples for major pathological correlate from inspiring English sources

Merely axonal injury is generally accepted to be the major pathological correlate of permanent disability in MS [18].

Here, we have evaluated whether laquinimod affects microglia directly, and whether this impacts neuronal/axonal injury that is a feature of MS and the major pathological correlate of disability in MS patients.

Besides the accumulation of soluble and insoluble Aβ, the intraneuronal abundance of hyperphosphorylated filamentous tau protein represents the second major pathological signature of AD [32] [34], which correlates well with cognitive impairment [35], [36].

Bevacizumab in combination with oxaliplatin/fluoropyrimidines can provide the highest major pathological response rate [15], and the pathological response to induction chemotherapy has been shown to correlate with improved survival [16].

The major pathological hallmarks of multiple sclerosis (MS) comprise inflammation, demyelination with associated gliosis and axonal damage, which most likely correlates with persisting disability.

ROS constitute a major pathological factor causing many serious diseases, including cancer and neurodegenerative disorders [32].

Only < 10% tumor cells were viable in all resected specimens, indicating major pathological response to alectinib.

The death of dopaminergic neurons is a major pathological hallmark of Parkinson's disease (PD).

Pathological examination revealed that only < 10% tumor cells were viable in all resected specimens, indicating major pathological response to alectinib (Fig. 3).

All images were screened for any major pathological changes.

Seven of 10 patients with PDA had major pathological responses.