Sentence examples for major pathological conditions from inspiring English sources

This review aims to acquaint the reader with the imaging anatomy of the PPF, its important communications, and to identify some major pathological conditions that can involve the PPF, especially in conditions where its involvement can have serious diagnostic and therapeutic implications, such as in perineural tumour spread.

Their clinical data are presented in table 1. Body Mass Index; 2 Visual Analogue Scale; 3 Quebec Back Pain Disability Scale; Multidimensional Pain Inventory Overall exclusion criteria were lumbar scoliosis, hip disorders, pregnancy within the last year, a history of central neurological impairments, and major pathological conditions such as a malignant tumour or uncontrolled systemic disease.

The integrin αvβ3 is expressed in a number of cell types and is thought to play a major role in several pathological conditions.

Same dose for Rg1 and Rb1 was adopted in the current study to better compare the effects of these two major saponins under complex pathological conditions.

Microglia and DCs are major APCs in physiological and pathological conditions, respectively.

We also demonstrate here the therapeutic potential of salubrinal for treating age-related disorders based on its ability to control MG-132 or CLP induced ubiquitin accumulation, ER stress and NFκB mediated inflammation, the major contributors of age-related pathological conditions.

Intestinal barrier dysfunction is one of the major contributing factors in multiple pathological conditions of the gastrointestinal tract.

The feet of patients with diabetes are at risk for ulceration due to a wide range of pathological conditions, the major three being peripheral neuropathy, foot deformity, and trauma, which may be exacerbated by comorbid peripheral vascular disease (4, 7).

Yet, in vivo, mammalian cells experience a wide range of oxygen concentrations, depending on the tissue type, proximity of cells to major arterioles and capillaries, and pathological conditions such as blood vessel occlusions, other sources of ischemia and neoplasia.

The enzymatic product of core α1,6-fucosyltransferase (FUT8) plays a major role in a plethora of pathological conditions, e.g. in prognosis of hepatocellular carcinoma and in colon cancer.

In order to fully realize this potential, it is necessary to critically assess the capabilities of current experimental methods in elucidating whether and how the mechanics of living cells and biomolecules, under physiological and pathological conditions, plays a major role in health and disease.