Sentence examples for major pathological component from inspiring English sources

ASM proliferation and migration is a major pathological component in airway remodeling of asthma.

Insufficient angiogenesis is a major pathological component of diseases such as chronic wounds and ischemic heart disease.

TAR DNA binding protein (TDP-43), encoded by the TARDBP gene on human chromosome 1, is a major pathological component of the neuronal inclusions associated with amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD-TDP) [ 28].

ROS constitute a major pathological factor causing many serious diseases, including cancer and neurodegenerative disorders [32].

In higher eukaryotes, major pathological cellular processes are associated with altered NPCs, and many viruses target components of the nucleocytoplasmic transport pathway to usurp it (Faustino et al. 2007; Chahine and Pierce 2009).

α-Synuclein is a pathological component of PD by participating in the Lewy body formation as the major constituent [8], [9].

Reduction of PVT1 expression by siRNA significantly affected mRNA and protein levels of all ECM components examined, suggesting that PVT1 contributes to ECM deposition in the glomeruli, one of the major pathological features of diabetic nephropathy.

Only < 10% tumor cells were viable in all resected specimens, indicating major pathological response to alectinib.

The death of dopaminergic neurons is a major pathological hallmark of Parkinson's disease (PD).

Pathological examination revealed that only < 10% tumor cells were viable in all resected specimens, indicating major pathological response to alectinib (Fig. 3).

Silicotic nodules are known as the major pathological character of silicosis.