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The major pathological characteristics of OA include progressive loss of articular cartilage, osteophyte formation, and changes in peri-articular and subchondral bone [ 1, 2].
The major pathological characteristics of AD brains are the presence of senile plaques composed of beta-amyloid peptide (Abeta), neurofibrillary tangles (NFT) formed by hyperphosphorylated tau protein, and neuronal loss (reviewed in [ 72, 73]).
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Therefore, white matter changes are a major pathological characteristic of FTD (Larsson et al., 2000, 2004).
25 High glucose concentration, a major pathological characteristic of diabetes, may have toxic effects on neurons in the brain through several mechanisms.
Mouse models in prion disease are particularly useful as unlike many other neurodegenerative diseases; mice are naturally susceptible to prions and faithfully mirror the clinical and pathological characteristics of the human disease, including the major genetic influence of Prnp.
Clinical and pathological characteristics of the patients were abstracted from hospital and pathology records.
They're in on the joke, and the joke is all there is: most of the evening is spent on endless illustration of the family's evident pathological characteristics.
These cytological and pathological characteristics are diagnostic for PAP.
ROS constitute a major pathological factor causing many serious diseases, including cancer and neurodegenerative disorders [32].
Only < 10% tumor cells were viable in all resected specimens, indicating major pathological response to alectinib.
The death of dopaminergic neurons is a major pathological hallmark of Parkinson's disease (PD).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com