Sentence examples for major pathological characteristic from inspiring English sources

Therefore, white matter changes are a major pathological characteristic of FTD (Larsson et al., 2000, 2004).

25 High glucose concentration, a major pathological characteristic of diabetes, may have toxic effects on neurons in the brain through several mechanisms.

The major pathological characteristics of OA include progressive loss of articular cartilage, osteophyte formation, and changes in peri-articular and subchondral bone [ 1, 2].

The major pathological characteristics of AD brains are the presence of senile plaques composed of beta-amyloid peptide (Abeta), neurofibrillary tangles (NFT) formed by hyperphosphorylated tau protein, and neuronal loss (reviewed in [ 72, 73]).

ROS constitute a major pathological factor causing many serious diseases, including cancer and neurodegenerative disorders [32].

Only < 10% tumor cells were viable in all resected specimens, indicating major pathological response to alectinib.

The death of dopaminergic neurons is a major pathological hallmark of Parkinson's disease (PD).

Pathological examination revealed that only < 10% tumor cells were viable in all resected specimens, indicating major pathological response to alectinib (Fig. 3).

A major pathological hallmark of AD is the deposition of insoluble extracellular β-amyloid (Aβ) plaques.

Silicotic nodules are known as the major pathological character of silicosis.

Instead small and soluble Aβ oligomers are suggested to exert the major pathological effects.