Sentence examples for major pathological changes from inspiring English sources

All images were screened for any major pathological changes.

Myocardial apoptosis is one of the major pathological changes of HF.

Ankylosis and joint angle malformation are major pathological changes in CIA, especially at the late stage of the disease [ 20].

Mice homozygous for Wa5 are embryonic lethal, but the heterozygotes are viable and show no major pathological changes, allowing for long-term studies.

Essentially, the major pathological changes in SpA are characterized by an aberrant bone formation that predominantly affects the spine and large joints asymmetrically [ 6, 7].

Major pathological changes in diabetic patients such as insulin resistance and high levels of glycated hemoglobin (HbA1c) have also been reported in smokers [ 7].

In AD, the accumulation of Aβ, especially Aβ42, is a major pathological change [7], [8], [36] and the abnormality in neuronal synchronization is well described [4], [5].

Dysfunction of any of the above steps will impair normal neurotransmission, which is indeed a major pathological change during the progression of AD [ 4– 6].

No major pathological change was found at necropsy or histopathology making it unlikely that the hyperbilirubinaemia was caused by liver damage.

As hypomyelination was the major pathological change in the peripheral nerves, we also determined the g-ratio in the ventral funiculus of the spinal cord.

On necropsy, no major gross pathological changes were observed in NR-INF-02 treated rats (Tables 7 and 8).