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Rupture of vulnerable atherosclerotic plaque is the major pathological cause of luminal thrombosis in acute coronary syndromes.
Preliminary studies of the major pathogen enterovirus 71 (EV71), a member of the Picornaviridae family, have suggested that EV71 may be a major pathological cause of fatal hand, foot and mouth disease cases by inducing significant pathological changes in the central nervous system (CNS) that ultimately lead to neurogenic pulmonary failure.
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ROS constitute a major pathological factor causing many serious diseases, including cancer and neurodegenerative disorders [32].
Twenty or 90 weeks of LMNA c.1824C>T mutation expression did not cause any major pathological changes in bone (Fig. 1U and Supplementary Material, Fig. S1A and B).
Our primary objective is to compare the accuracy of post-mortem imaging combined with guided biopsy for the detection of the cause of death and/or major pathological lesions to that of conventional autopsy in foetuses, newborns and infants.
To compare the accuracy of whole body post mortem MR imaging for detecting the cause of death and/or major pathological lesions with that of conventional autopsy in fetuses, newborns and children.
MI remains the major cause of death in the developed world and is a major pathological issue worldwide despite rapid advancements made in the treatment of coronary artery diseases (CAD) [ 6].
No major pathological change was found at necropsy or histopathology making it unlikely that the hyperbilirubinaemia was caused by liver damage.
The exact cause(s) of psoriasis is are) not fully understood; but it is now accepted that there are three major pathological steps in its development: epidermal hyperproliferation, inflammatory infiltration of epidermis and dermis, and pathological neovasculature.
Again, the evidence suggests a common pathological cause.
Only < 10% tumor cells were viable in all resected specimens, indicating major pathological response to alectinib.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com