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In this disease, it was recently shown that the major pathological alterations of the central retina occur mainly proximal to the photoreceptor layer [15].
Human data are very rare (Tsuji et al., 2000) and provide only limited information on major pathological alterations.
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Chronic selenium toxicity was found in fish community including symptoms like telangiectasia (swelling) of gill lamellae, reduced hematocrit and hemoglobin levels, corneal cataracts, pathological alterations in major organs, reproductive failure, and teratogenic deformities [95].
Thus, we can expect to unmask pathological alterations in the majority of our patients.
Currently, three major mechanisms have emerged that encompass most of the pathological alterations observed in the vasculature of diabetic animals and humans: 1) Nonenzymatic glycosylation of proteins and lipids 2) oxidative stress 3) protein kinase C (PKC) activation.
Although the profound structural impairment of astrocytes is well documented in the lesions of patients with NMO, potential pathological alterations of astrocytes in MS lesions have not received major attention.
DMN administration induced severe liver pathological alterations.
Pathological alterations of the cornea strongly affect the eye power.
Aged black garlic succeeded in protecting the liver from apoptosis and pathological alterations induced by CP.
No evidence exists regarding the sublethal effects of cyanotoxins, including pathological alterations.
In addition, histopathological analysis was also carried out to mark the pathological alterations.
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