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S. sclerotiorum infection significantly inhibited photosynthesis, which suggests that the photosynthetic apparatus is a major pathogenic target.
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Thus, systemic TGF-β antagonism seems to target the disease-specific major pathogenic immune effector cells in inflammatory lesions without affecting systemic immune homeostasis.
Thus, there is a need for highly prioritized shortlists of potential targets directly linked to major pathogenic processes.
Bacillus remains the major pathogenic bacterium isolated in majority of areas for Bombyx mori [17].
The implication of autophagy in two major pathogenic pathways in SLE suggests the potential to use inhibition of autophagy as a novel treatment target in this frequently severe autoimmune disease.
The second section targets MCL-1, an antiapoptotic BCL-2 family protein that has emerged as a major pathogenic factor in human cancer.
Two major pathogenic pathways have been established in these syndromes: hypoxia pathway (VHL and PGL syndromes) and the pathway involving Ras and mechanistic target of rapamycin (mTOR) activation (MEN2 and NF1).
From this joint effort, major pathogenic pathways emerged.
Oxidative stress is a major pathogenic mechanism of lead neurotoxicity.
The protein toxins are major pathogenic factors and causally involved in various diseases induced by Clostridia.
Immunological dysregulation is now recognised as a major pathogenic event in sepsis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com