Sentence examples for major pathogenic role from inspiring English sources

The degenerated bony structure of the lumbar spine and the facet joints suggest a major pathogenic role of degenerative segmental instability in pseudocyst formation of the ligamentum flavum, as found by other authors too [18].

There is a suggestion that fetuin-A constitutes a link between obesity, insulin resistance and NAFLD, plays a major pathogenic role in metabolic disease (Mori et al., 2011, Pal et al., 2012, Stefan and Haring, 2013).

Oxidative stress is believed to play a major pathogenic role in retinal degeneration as found in diabetic retinopathy and AMD.

Additonally, minimal Th17 cells were found in wt or IL-6KO mice, as measured by expression of the Th17 specific transcription factor RORγt at day 10 PI, regardless of the treatment (Figure 7b, Figure S4b) suggesting that Th17 cells do not play a major pathogenic role in viral-mediated autoimmune myocarditis development.

Hypoxia plays a major pathogenic role in diabetic nephropathy (DN).

In MS lesions, oxidative stress appears to play a major pathogenic role.

Although Aβ peptides longer than Aβ42 are found in AD, they are not a major species and their pathogenic role has been ignored.

Major points regarding the potential pathogenic role for each of these factors and processes are further discussed in the following sections.

The association with HLA B27 and CD8 T-lymphocyte function also supports a potential pathogenic role as the major histocompatibility complex class I molecules may present arthritogenic peptides to CD8+ T lymphocytes or select an autoreactive T-cell repertoire.

Although the etiology of UC, the major form of IBD, remains unknown, the pathogenic role of the intestinal microvascular involvement has been recently highlighted.

Bacillus remains the major pathogenic bacterium isolated in majority of areas for Bombyx mori [17].