Sentence examples for major pathogenic factor from inspiring English sources

The second section targets MCL-1, an antiapoptotic BCL-2 family protein that has emerged as a major pathogenic factor in human cancer.

Overload of the wrist extensors, which is considered to be a major pathogenic factor in lateral epicondylitis, can be reduced by braces.

Undesired activation of the complement system, a part of the immune system, is a major pathogenic factor contributing to various diseases, such as ischemia-reperfusion injury, sepsis, asthma, allergic reactions, rheumatoid arthritis, Alzheimer's disease, myasthenia, multiple sclerosis and others.

Microvascular disease is a major pathogenic factor for chronic kidney disease (CKD) in persons with diabetes, but the role of microvascular disease in the development of CKD in the general population is unclear.

Aims: The present study was designed to evaluate the oxidative stress as the major pathogenic factor of reflux esophagitis and the importance of antioxidant in treatment of reflux esophagitis.

The present study was designed either to evaluate the oxidative stress as the major pathogenic factor of reflux esophagitis or to find out the usefulness of antioxidant in the treatment of reflux esophagitis and the prevention of development of Barrett's esophagus.

The protein toxins are major pathogenic factors and causally involved in various diseases induced by Clostridia.

Comparable NLRP3-driven reaction patterns have been realized as major pathogenic factors of serious diseases of civilization.

Bacterial lipopolysaccharide (LPS) is believed to be one of the major pathogenic factors of Gram-negative sepsis.

Since advanced glycation end products (AGEs) are major pathogenic factors and active inflammation inducers in diabetes mellitus, this study assessed the effects of AGEs on macrophage polarization.

PPROM, defined as rupture of the membranes before 37 weeks of gestation, contains two major pathogenic factors, membrane rupture and preterm labor [ 50, 51].