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Historically, the Aβ42 fibers have been considered to be the major pathogenic agents of AD.
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The filamentous ascomycete Fusarium graminearum (teleomorph Gibberella zeae) is the major pathogenic agent of Fusarium head blight(FHB) [1], which can cause diseases for wheat, barley and other crops, and is becoming a serious disease in many countries over the world.
We recently described the possibility of a causal relationship between LCH and dermotropic Merkel cell polyomavirus (MCPyV) [ 92], which was discovered as the major pathogenic agent in Merkel cell carcinoma of the skin in 2008 [ 93].
This result further suggests that cigarette smoking may not be the major pathogenic agent involved in the initiation of lung AC but that some as-yet-unidentified carcinogens may have played a major role in the development of lung AC in this study population.
Database URL: http://csb.shu.edu.cn/efg/ The filamentous ascomycete Fusarium graminearum (teleomorph Gibberella zeae) is the major pathogenic agent of Fusarium head blight (FHB) and Fusarium ear rot (1), which can cause diseases for wheat, barley, maize and other crops, leading to yield loss and food quality problems, and are becoming serious problems in many countries over the world.
The major pathogenic factor of DM is hyperglycemia, which is a significant contributor to the accumulation of AGEs [13, 63].
To date, increased fat consumption is considered the major pathogenic factor of MS and NAFLD.
These data confirm that TNF, apparently, is not a major pathogenic factor in pSS.
The complement system is a major innate defense system against various pathogenic agents, including bacteria and viruses.
Bacillus remains the major pathogenic bacterium isolated in majority of areas for Bombyx mori [17].
The prevalence of the different causative pathogens seemed to be age stratified with Haemophilus influenzae or Staphylococcus aureus being considered as pathogenic agents in the early life and Pseudomonas aeruginosa or Burkholderia cepacia complex (Bcc) being the major opportunistic pathogens during adulthood [3].
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