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Their formation remains a major open question.
Exactly how this happens is a major open question in cognitive neuroscience.
Their formation atop of the cratonic lithosphere in the interior of East Antarctica remains a major open question.
A major open question in natural language research is the role of communicative efficiency in the origin and on-line processing of language structures.
The major open question is whether there is a global ocean of liquid water beneath Europa's ice, warmed by the release of tidal energy in Europa's interior.
A major open question regards the receptor and signaling cascade as well as the roles of the Dkk3/sgy subfamily, which is still poorly understood.
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As a consequence, major open questions on the internal structure of the belt have remained unsolved.
Major open questions and suggestions for future research priorities are outlined.
I would like to introduce some of the major open questions.
A well-supported and detailed phylogenetic framework is critical to the solution of major open questions such as the evolutionary origin of multicellularity, diversification of life-history strategies, the conquest of land, the nature of the relationship between ontogeny and phylogeny, and modes of evolution at the molecular level.
Certain major open questions in logic and theoretical computer science can be formulated in terms of IFL.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com