Sentence examples for major obstacle to the implementation of from inspiring English sources

The major obstacle to the implementation of cost-effective control is the lack of accurate descriptions of the geographical distribution of infection.

In Africa, the practice of mixed feeding, often from a very young age [ 13] has been observed to be a major obstacle to the implementation of this guideline [ 14- 16].

In fact a precise biochemical diagnosis facilitates immensly the interpretation of genomic data, which at present is still a major obstacle to the implementation of exome sequencing for routine diagnosis.

Concerning future developments, the jury of the Consensus Conference offers the following comments: ● Current lack of knowledge concerning the epidemiology of severe ARDS in France constitutes a major obstacle to the implementation of a reasoned strategy for use of extracorporeal life support techniques, notably ECMO.

One major obstacle to the implementation of 'networked genomic medicine' will be privacy concerns, as there are many cultural, political and legal obstacles to the sharing of genetic data, only some of which have been partially alleviated in the USA with the Genetic Information Nondiscrimination Act of 2008.

One of the major obstacles to the implementation of clinical protocols using the various Tregs is the low frequency of Tregs in the peripheral blood, which necessitates ex vivo multiplication of the cells prior to their use in vivo.

National guidelines, budget ceilings, interference from higher authorities, unreliable and untimely disbursement of funds, inactive grassroots participatory structures, and low awareness of health staff, stakeholders and communities were the major obstacles to the implementation of the Accountability for Reasonableness intervention.

Despite many efforts and substantial progress, a further major obstacle to the practical implementation of spintronics is the lack of a proper understanding of spin transport and dynamics in semiconductor-based heterostructures [3].

Immune responses to therapeutic proteins and clearance of corrected cells is a major obstacle to the clinical implementation of gene therapy.

Fluid handling has been a major obstacle to the full implementation of miniaturized assays.

However, limited availability of islet donors, high rates of graft failure and the need of life-long nonspecific immunosuppressive therapy of the receptor have been major obstacles to the widespread implementation of this treatment [9].