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In addition, we found that the presence of PIK3CA major mutations of cfDNA was associated with PI3K pathway‐dependent AR phosphorylation.
In conclusion, we showed that the presence of PIK3CA major mutations of cfDNA could be a discriminatory predictor of RFS and BCSS.
We demonstrated that the presence of PIK 3 CA major mutations of cf DNA could be a discriminatory predictor of RFS and BCSS in early‐stage TNBC patients and it was associated with PI3K pathway‐dependent AR phosphorylation.
We demonstrated the presence of PIK3CA major mutations of cfDNA could be discriminatory predictor of RFS and BCSS in early‐stage TNBC patients which may be associated with PI3K pathway dependent AR phosphorylation.
Locomotor activity was used to detect possible behavioral effects or disruption of the circadian system, although imaging of hypothalamic explant cultures from the fos::luc and CMV::luc mice has shown circadian rhythms in transgene expression [ 14, 35], so it was unlikely that the mice had major mutations of the circadian system.
Similar(55)
In addition to these major mutations, some of the strains showed C58A, T66G, G81T, A140C, and A209T mutations of L4, and C62A and T65A mutations of L22, further causing the changes of encoded amino acids.
Present mutagenicity tests have concentrated on discrete major mutations, while mutations of polygenes, acting on quantitative characters, have largely been omitted.
DNA sequencing has revealed the presence of major mutations in the genes responsible for the emergence of resistance to the major anti-TB drugs.
Ever since Erasmus, if not before, the favored approach to reconstructing a text has been first to reconstruct the "family tree" (stemma) of manuscripts based on the occurrence of major "mutations" (characteristic errors) [4].
Scientists are reporting a significant milestone for cancer research after charting 21 major mutations behind the vast majority of tumours.
The topology of the dendrogram shows the existence of one significant (bootstrap > 0.75) cluster of major mutations in newly diagnosed HIV-1 B subtype infected patients.
Related(20)
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