Sentence examples for major mutation from inspiring English sources

Within this motif, Gly and Gly (Gly and Gly in RRAS) represent major mutation hot-spots in human cancer (COSMIC database) and account for the majority of germline HRAS mutations causing Costello syndrome (20).

The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots.

In general, the average VAF of major mutation clusters substantially decreased after platinum treatment, possibly reflecting the decrease in tumor burden with treatment in these patients.

Cuajungco, M. P. et al. Tissue-specific reduction in splicing efficiency of IKBKAP due to the major mutation associated with familial dysautonomia.

G C > T A transversion and G C > A T transition are the major mutation types.

This indicated that SNPs was the major mutation type causing phenotypic differences between GXA-28 and GXG-5.

Scientists are reporting a significant milestone for cancer research after charting 21 major mutations behind the vast majority of tumours.

Two major mutations (C282Y and H63D) were determined for each patient.

"We finally know what the major pathways are and what all the major mutations look like".

Then, for reasons not understood, two major mutations made one receptor sensitive just to cortisol, leading to the modern version of the stress hormone receptor.

Last week, the federal Centers for Disease Control and Prevention released a study that found that only 52percentt of health care providers in five United States cities knew that the major mutations for breast cancer could be inherited from either parent.