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The normal expression of the major molecules involved in cell death and survival (data not shown) and the normal apoptosis of thymocytes in the thymus indicate that the abnormalities resulting from sustained Egr-2 expression are not due to increased apoptosis.
The major molecules involved in the NHEJ pathway are heterodimeric DNA end-binding complexes Ku86/Ku70 [ 14].
Enamelysin (Mmp20), a matrix metalloproteinase, and Kallikrein (Klk4), a serine protease, are two major molecules involved in this process.
Because of their abundance and their ability to protect plants against biotic stresses, PAs and flavan-3-ols might be the major molecules involved in grape embryo protection.
Now that the major molecules involved in the process are identified and with the knowledge that maintenance of a single CpG island in a ZFP57 binding site ensures the maintenance of imprinting, the experimental paradigm shifts.
MT1-MMP and uPAR are the major molecules involved in the activation of MMPs and their expression has been shown to correlate with metastatic and invasive potential of several cancers [ 20– 20].
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As integrins are major adhesion molecules involved in cell-ECM interactions, we studied the effects of ITG α5 on cell matrix adhesion.
Furthermore, to assess fiber type-specific absolute total and phosphorylated concentrations of the major signaling molecules involved in muscle protein turnover, quantitative immunohistological methods or in situ hybridizations (van Beek-Harmsen et al. 2004; van Beek-Harmsen and van der Laarse 2005) are required.
GSH is a three-amino acid peptide and serves as the major antioxidant as well as the major endogenous molecule involved in the detoxification of the biological system.
Heterotrimeric G-proteins, a major group of signaling molecules involved in a variety of cellular activities in mammals, are mainly responsible for various cellular responses to external signals.
P is critical to a variety of plant functions [e.g., RuBP regeneration; 28] and is a major component of key molecules involved in photosynthesis, including phospholipids, nucleic acids, sugar phosphates, and ATP [29].
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