Sentence examples for major molecular subgroups from inspiring English sources

Two major molecular subgroups of CRC have been discerned – MSS and MSI cancers.

Studies confirmed that it could reliably identify the major molecular subgroups of invasive breast carcinoma [ 14- 16].

With these recent advances, virtually all cases of FTLD can now be assigned to one of the three major molecular subgroups (FTLD-tau, FTLD-TDP or FTLD-FUS).

Two major molecular subgroups of colon cancer exist, microsatellite instable (MSI) and microsatellite stable (MSS) (Fearon and Vogelstein, 1990; Lengauer et al, 1997), where MSI tumours represent approximately 15% of the total incidence (Clark et al, 2004).

Importantly, definitions of the histopathological and molecular subgroups of the reference tumors will dramatically influence the classifiers, possibly requiring major changes and improvements to existing disease classifications.

Four major molecular subtypes of medulloblastoma with distinct biological, clinical and pathological features are now recognised, and this subgrouping is beginning to have clinical impact [ 1- 3].

Similarly, we identified distinct molecular subgroups of BRAF-mutant tumors, and multidimensional analyses highlighted a potential involvement of oncomiRs in less-differentiated subgroups.

CDPs portray the diversity calculated with three major molecular representations: molecular scaffolds, fingerprints, and physicochemical properties.

Three distinct molecular subgroups of ATRTs, associated with differences in demographics, tumor location, and type of SMARCB1 alterations, were identified.

Genetic analyses of the tumor suppressor gene SMARCB1 (FISH, MLPA, sequencing) and Illumina 450 k methylation profiling segregated molecular subgroups.

Moreover, an integrated genomic analysis of these two histological subtypes by The Cancer Genome Atlas has led to their molecular reclassification into four discrete molecular subgroups.