Sentence examples for major molecular pathways from inspiring English sources

Molecular targeted therapy is designed to inhibit the major molecular pathways identified as essential for a specific development.

To investigate this complex host response, we studied the whole transcriptional activity of patient valves in the attempt to identify the major molecular pathways involved in IE pathophysiology.

For each time point several major molecular pathways were identified.

Colorectal cancers (CRCs) arise through two major molecular pathways.

To identify the major molecular pathways affected in each condition, Ingenuity Pathway Analysis (IPA) was performed.

Conceivably, one of the major molecular pathways involved in RCC pathogenesis is the Hh signalling pathway.

These results represent the first characterized major molecular pathway that regulates fragile site expression.

This is a major molecular pathway for hypoxia-driven angiogenesis.

PI 3-kinase pathway is pivotal in the regulation of EPC proliferation, recruitment and mobilization and its impairment in insulin resistance states seems to be a major molecular pathway implicated in reduced EPC counts and increased arterial stiffness [ 15].

Importantly, sarcomere architecture is almost identical between C. elegans and mammals (16) and many of the major molecular signaling pathways (17) and muscle protein degradation pathways (18) are present in both systems.

Those individuals that do survive generally have non-syndromic HPE, with fourteen dominant loci currently identified in association with these forms, collectively encoding proteins functioning within four of the major molecular signaling pathways (Bone Morphogenetic Protein, Fibroblast Growth Factor, Nodal and Hedgehog) (Bae et al., 2011; Roessler and Muenke, 2010).