Sentence examples for major methodological limitations from inspiring English sources

Most of the phase III trials on AEDs in children have major methodological limitations that considerably limit meaningful conclusions about comparative efficacy between old and new molecules.

However, several major methodological limitations prevent clear conclusions.

All the studies assessing clozapine treatment for TD have major methodological limitations, so no final conclusion can be drawn.

However several techniques, namely yoga, relaxation and other forms of meditation do not appear to reduce blood pressure, and there are major methodological limitations with many studies of stress reduction techniques.

However, that study suffered from major methodological limitations.

There were two major methodological limitations in the current study.

A major methodological limitation of current studies has been a reliance on retrospective reporting of functioning and use of samples of individuals who have self-selected for participant in grief research.

A major methodological limitation of this study is the data extraction protocol, because the classification of papers as positive and negative was not blind to the papers' discipline and methodology.

A major methodological limitation of this study was that it was not conducted across different studies.

The major methodological limitation of the present study is the cross-sectional design, which does not permit causal inferences to be made.

Although we obtained accurate data and successfully implemented a system of early detection for breast cancer, the major methodological limitation of this study was that we failed to separate symptomatic from asymptomatic women.