Sentence examples for major methodological issues from inspiring English sources

While the number of publications increased recently, major methodological issues were still evidenced.

One of the major methodological issues which arises when quantitatively comparing DRG systems across countries, is variation in purchasing power between nations.

The reliability and validity of pressure ulcer diagnosis and grading are major methodological issues in studies and reports on pressure ulcer frequency.

Developing objective markers of the transition between EPIS stages rather than relying on assumptions about how long each stage should last (e.g., conflating study timeline with site progression toward sustainment) was one of the major methodological issues that had to be resolved in applying and rigorously testing the EPIS framework.

In conclusion, in this study of school age Canadian students we addressed two major methodological issues of social epidemiological research: the validity of composite community level measures and the possibility of structural confounding.

In this analysis, we address two major methodological issues concerning the use of caregivers as proxies for children's HRQOL measures, and the use of different HRQOL instruments across health conditions in young patients.

One major methodological issue is the difficulty of finding universally applicable paradigms that can be standardized and that are ecologically valid for the species to be compared.

Based on our experience as ophthalmologists, the major methodological issue that may cause a bias is, to our opinion, the way the assessment of the visual acuity was conducted.

Methodological issues focus on major variables that influence exposure or its detection through disruptions of behavior, neuroanatomy, or neurochemical end points.

The one-hundred and three papers in this special issue highlight the major methodological developments and controversies of fMRI from a first person perspective over the past twenty years.

In the Discussion sections we again rated coverage of methodological issues, efficacy, and safety/toxicity as none, minimal, substantial, or the major focus of the section.