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During wine fermentation, the evolved strains displayed major metabolic changes, such as lower levels of acetate production, higher fermentation rates and enhanced production of aroma compounds.
Overall, we found major metabolic changes that confirm previous studies, but also reveal new insights into the physiology and regulation of developmental diapause in Nasonia, which showcases how non-gel shotgun proteomics can be used to map underpinnings of this syndrome.
Major metabolic changes are also observed in cancers [ 72, 88, 128, 129].
The major metabolic changes were confirmed by chemical, transcriptional, physiological and biochemical experiments.
The former is associated with physiological decline, while fasting for short periods (∼24 hr) leads to major metabolic changes.
Moreover, single amino acid changes in rpoB have been associated with major metabolic changes in the same organism, enabling the utilization of diverse substrates that had not previously been identified as suitable for supporting growth.
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"Too often, though, their mind is elsewhere -- and speed, incline and overall intensity is far too low to affect major metabolic change," she says.
A major metabolic change exhibited by the PPARδ treated skeletal muscle was a decrease in the concentration of the majority of the observed amino acids.
A major metabolic reprogramming change that occurs in most malignant cancer cells is the shift in energy metabolism from oxidative phosphorylation to aerobic glycolysis (the Warburg effect) [ 3].
The two-step process during which the cells undergo major metabolic and biochemical changes demands considerable energy input both by the process operators and by the algae.
LD skeletal muscle development from the late fetal state to postnatal life was associated with a remarkable transition in the gene expression program, which probably underpinned major metabolic and structural changes.
More suggestions(15)
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