Sentence examples for major mechanisms regulating from inspiring English sources
Coordinated transcriptional control of genes is one of the major mechanisms regulating various processes [ 12].
Epigenetic alterations, including DNA methylation and histone modifications, emerges as one of the major mechanisms regulating miRNA expression.
FAS and TCR restimulation mediated death constitute two of the major mechanisms regulating T cell survival and homeostasis [ 12- 14].
In kinetoplastids, one of the major mechanisms regulating gene expression is at the level of translation [ 38], thus the presence of mRNA does not systematically account for the expression of the corresponding protein.
Histone modifications are one of the major mechanisms regulating gene expression, acting in combination with other mechanisms such as alternative promoter usage [ 2], alternative splicing [ 3], and microRNAs [ 4].
Two major mechanisms regulate activated (cleaved) PAR, namely desensitization or receptor trafficking [ 32].
We found that enhanced expression of MKP7 is a major mechanism regulating lifespan and senescence.
In particular, differential FASL expression between Th1 and Th17 cells is the major mechanism regulating their differential cell death sensitivity.
Because destabilization through proline hydroxylation and subsequent degradation through the proteasome is a major mechanism regulating HIF1α levels, we first examined whether WRN depletion affects HIF1α protein stability.
Over the past decade, alternative splicing has been progressively recognized as a major mechanism regulating gene expression patterns in different tissues and disease states through the generation of multiple mRNAs from the same gene transcript.
Indeed, in addition to transcriptional control, considered to be the major mechanism regulating E-cadherin expression, recent data also suggest that post-translational mechanisms, such as ubiquitination, endocytosis and lysosomal degradation of E-cadherin, occur during EMT, and are important for both embryological development and tumour progression [ 53, 54].
