Sentence examples for major mechanisms causing from inspiring English sources

Inflammatory process and oxidative stress are thought to be the major mechanisms causing I/R.

While factors that mediate tumor angiogenesis have been well defined [ 7, 25, 51, 56], the major mechanisms causing non-angiogenic, invasive tumor growth in vivo still remain elusive.

Decomposing analysis indicated that Stokes transport is the major mechanism causing this particular residual transport pattern.

Therefore, LINE-1 retrotransposition may not be the major mechanism causing somatic mutation in cancer by global hypomethylation.

Non-allelic homologous recombination between paralogous repeats is increasingly being recognized as a major mechanism causing both pathogenic microdeletions and duplications, and structural polymorphism in the human genome.

There is evidence pointing to excessive ROS production as a major mechanism causing damage in MS, as oxidized DNA, lipids and proteins were reported in CNS lesions, cerebrospinal fluid and plasma of MS patients [ 17, 21, 31].

One of the chronic consequences of hyperglycaemia is the accelerated formation of advanced glycation end products (AGEs), which are suggested as one of the major pathogenic mechanisms causing end organ damage in diabetes [ 1, 2].

The CmeABC multidrug efflux pump has been described as the major efflux mechanism causing antimicrobial resistance to several antimicrobials including the fluoroquinolones and macrolides [ 26, 27].

The relief of residual thermal stress and increases in the frictional resistance and anchor effect at the fiber bundle interface were considered to be the major mechanisms that caused the enhancements.

Three major mechanisms may cause genetic changes under laboratory rearing conditions: random drift, inbreeding and selection (Hopper et al. 1993).

Microaspiration of the gastro-oesophageal refluate and subsequent airway inflammation, are the major mechanisms that cause respiratory symptoms in GERD patients [ 33- 35].