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Although lymphocytes are transported via blood, the spleen is the major lymphoid tissue associated with the clearance of blood-borne antigens (Press and Evensen 1999; Whyte 2007).
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Therefore, cecum including cecal tonsil (one of major lymphoid tissues interacting with C. jejuni) at day 7 pi were collected to elucidate underlining mechanisms affecting resistance and the local host response to C. jejuni colonization.
We then identified the basis of this host response in 'optimal' iWT compared to 'non-optimal' iCT frogs by profiling the changes in the host transcriptome for early (day 7) and late (day 42) infections in the major amphibian lymphoid tissue, the spleen.
Since the spleen is a major peripheral lymphoid tissue, we performed quantitative RT-PCR analysis on splenocytes derived from 4-week-old, pre-diabetic NOD mice, with or without CFA treatment, to investigate the presence of IL-22-producing Th17 cells during autoimmune insulitis.
32 33 Thus, in major peripheral lymphoid tissues like spleen and lymph node, SHIP-deficiency leads to profound and functional expansion of immunoregulatory capacity.
Bronchus-associated lymphoid tissue has major morphologic and functional similarities to Peyer's patches found in the gut.
In conclusion, the CD44+ lymphoma cell lines expressed mainly CD44s, which as major splice variant of normal lymphoid tissue is believed to exert tumor suppressor functions.
To achieve this, we produced antibodies specific for Tasmanian devil CD4, CD8α, IgM, and IgG and used them in immunohistochemistry to characterize the presence of B cells and two major T cell subsets in lymphoid tissue and DFTD tumors.
The gut-associated lymphoid tissue is a major site of human immunodeficiency virus (HIV) activity and significantly influences disease prognosis.
Bone marrow is a major haematopoietic organ and a primary lymphoid tissue, besides it's considered to be an important storage of parasites in Leishmania-infected dogs.
In addition to viral burden, lymphoid tissue is the major site of HIV production in the body.
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