Sentence examples for major locus model from inspiring English sources

Elston et al. [ 17] outlined the criteria that must be satisfied before acceptance of the single major locus model so as to reduce the risk of false positive declarations of a major locus model.

Taken together, these results show that the no major locus model provides a plausible explanation for the inheritance of deafness in the JRT.

An outline of the criteria that must be satisfied before acceptance of the single major locus model has been provided [ 27].

Accordingly, for our suggested major locus model one would predict that 24% of dogs would be affected with Addison's disease in a randomly mating population.

This conclusion is based upon the 95% HDR shown for both the general major locus model and the completely recessive major locus model in Table 4, where the estimate of the variance attributable to the putative major locus includes zero (0.0).

For this reason we accept the conclusion of the simplest null model that of the major locus model with alleles moving from parent to offspring with the typically expected probabilities.

A second demonstration of the failure of each of these major locus models to provide an adequate explanation of the patterns of inheritance of deafness is that the 95% HDR for the allele frequency includes the value 1.0.

The null model is Mendelian transmission, and this model should be a significant improvement for the likelihood over the no-major locus model if we are to draw the conclusion that a major locus is segregating in this population of dogs.

In the second 5-locus model, the effects of alleles at four loci were additive, but a fifth locus had a major effect on the color and allele 1 was dominant at this locus (one major epistatic locus model).

It should be noted that the nuclear single major gene locus model is included as a special case in the assumptions.

Speciation was slightly more likely with the "100-additive-loci model" and with a "one major epistatic locus model" for male nuptial color, than with the "5-additive-loci model".