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Finally, one could imagine that, while Pher is the major locus determining the Z-, E- or H-type of the pheromone, Am is a 'secondary' locus marginally modifying the proportion of E and Z isomers in the blend.
In conclusion, the major locus determining familial longevity up to high age as detected by GWAS was marked by rs2075650, which tags the deleterious effects of the ApoE ε4 allele.
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These findings suggest that any underlying genetic susceptibility to RAM is likely to be mediated through the co-inheritance of multiple risk alleles rather than a single major gene locus determining radiosensitivity.
Vasa Nicotera, M. et al. Mapping of a major locus that determines telomere length in humans.
18 A recent genetic study in humans has further implicated vitamin D as a strong environmental candidate by showing direct functional interaction with the major locus that determines susceptibility to multiple sclerosis.
First, we identify an inversion at the locus determining seed coat color during domestication.
Locus determining normal colony formation on the chromosome of Escherichia coli K-12.
There is also the benefit that the major loci that determine the polymorphism show simple Mendelian inheritance (Cook 1967; Jones et al. 1977).
Menon, M. C. et al. Intronic locus determines SHROOM3 expression and potentiates renal allograft fibrosis.
This requires linkage disequilibrium to build up between loci determining resource use and loci determining mating preference.
A major sex determining locus was mapped to linkage group 13 in both families.
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