Genome wide association tests for three fruit traits revealed associations with SNP in two intervals surrounding previously described QTL for fruit shape and locule number on chromosome 2. Results from association highlighted two previously identified major loci accounting for fruit shape and size variation, namely LC and OVATE.
Roughly five major loci account for the very dramatic morphological differences between teosinte and modern maize (Doebley and Stec 1993).
Overall, the preponderance of data suggest that no single major locus can account for the majority of the familial aggregation of TGCT, but rather that multiple susceptibility loci with weak effects appear to be involved (Crockford et al, 2006).
The genetic analysis of ACE has revealed an important insertion (I /deletion (D) polymorphism, a 287 bp DNA sequence in the intron 16 of chromosome 17 in the ACE gene, a major locus that accounts for approximately 50% of the total phenotypic variance of circulating and tissue ACE (Rigat et al, 1990).
The qPH-8.2 and qPH-3.3 QTLs were the two major loci that accounted for 23.03 and 18.07 % of the sesame PH variation, respectively.
Two major QTLs, and two minor loci accounting for about one half of the phenotypic variation have been identified through our quantitative analysis, suggesting that a few major mechanisms are controlling partial resistance to Pst.
The genetic basis of inherited susceptibility to lung cancer outside the context of the rare Mendelian cancer predisposition syndromes is at present undefined, but a model in which major gene loci account for the excess familial risk seems unlikely.
The major locus at 72 Mb on BTA6 accounted for 43.75% of genetic variation using BayesB procedures with π ^ = 0.995.
Fitting breed-of-origin of the 1 Mb region that contains these three genes in the model accounted for the majority of variation attributed to the major locus.
Fitting SNP haplotypes for a 1 Mb interval that contained all three genes and centered on KIT accounted for the majority of the variation attributed to this major locus, which suggests that one of these genes or associated regulatory elements, is responsible for the majority of variation in degree of reddening.
