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However, the fast rate of corrosion of magnesium remains one of the major limitations of using Mg and Mg alloys as implants.
At the moment, since cytoplasmic TDP-43 inclusions are only found in post-mortem CNS tissues, there are two major limitations of using TDP-43 as a potential biomarker of the disease.
There are major limitations of using 25(OH D as a status biomarker, including the unknown extent of storage of vitamin D, potential dangers of its accumulation in adipose tissue, regulation of its mobilization from these stores, and the consequences of the saturation of this storage.
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The major limitation of using static elements is the inability of independent control of each trap or a region of traps.
Although the major limitation of using crumb rubber as aggregate in the concrete is to reduce the compressive strength, the results reached were higher than 40 MPa for the paving blocks with the inclusion of 50% of crumb rubber.
The major limitation of using the constant phase model is that when airway constriction is heterogeneous it creates amplified frequency dependence in both R L and in E L (see "Forward modeling" section).
The major limitation of using mutants for functional genomics research is the absence of detectable (visible) phenotypes for most mutants even when the disrupted gene(s) in a mutant line is known.
With this method the major limitation of using PAA templates is overcome by selectively removing the dendritic ends, formed due to the inherent barrier layer thinning step required for nanowires growth.
Until the mid-1990s, a major limitation of using the Universal Soil Loss Equation and Revised Universal Soil Loss Equation erosion models at regional landscape scales was the difficulty in estimating LS factor (slope length and steepness) values suitable for use in geographic information systems applications.
The major limitation of using these methods is the expense of identifying large numbers of subjects with and without the full spectrum of the primary trait.
A major limitation of using reporter genes for viral vector tracking and tropism is that only those viruses or vectors that are successful are tracked.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com