Sentence examples for major limitations include from inspiring English sources

Major limitations include their high cost and brittleness, traits which have hindered the commercial adoption of this technology.

Major limitations include accessibility of the epitope, size limitations, perturbation of the structure of the viral protein by the inserted epitope, and enforcement of a non-native structure on the epitope.

Major limitations include the following.

Major limitations include nonrandomization of villages in the baseline study and losses to follow-up.

Major limitations include small numbers and the fact that diagnoses of the suicide victims are based on data accrued by proxy interviews.

Major limitations include the still rather substantial exclusions of patients notified by DCO and the limited information on key prognostic variables, in particular stage at diagnosis.

A few field-deployable assays (strip or lateral-flow immunoassays) are available but suffer from major limitations including poor detection limit and inability to provide quantitative results.

Prevention relies on vaccination which has several major limitations including the lag time for vaccine preparation and the low vaccination coverage rate.

That study had a number of major limitations, including the control subjects having no radiographic evaluation, incomplete evaluation of OA subjects, and only 12 months of follow-up.

Conventional methods for time-location collections (e.g. self-reported paper diary and telephone interview) have several major limitations, including omission of short trips and inaccurate reporting of trip duration [ 27, 28].

Epigenetic drugs available now such as azacitidine and decitabine or those currently being researched in vitro have major limitations, including lack of specificity and efficacy (Ptak and Petronis, 2008, Cantley and Haynes, 2013).