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Long corrosion period and slow resorption in vivo remain major limitations for iron-based bioresorbable scaffolds.
Abiotic environmental stresses such as drought, salinity and low temperature are major limitations for plant growth and crop productivity.
The development of resistance is one of the major limitations for the use of platinum (Pt) complexes in cancer chemotherapy.
Major limitations for the procedure include donor organ shortage, high cost, high level of required expertise, and long-term consequences of immune suppression.
The major limitations for the production of PHB are requirement of special growth conditions, difficulty associated with production from inexpensive precursors and high recovery cost.
One of the major limitations for efficient conversion of plant biomass to biofuels is the recalcitrant nature of the plant cell wall, which is composed mostly of lignocellulosic materials (lignin, cellulose, and hemicellulose).
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However, the extent of polymorphism detected in our candidates was very limited and thus might not create a major limitation for vaccine efficiency.
The heterogeneity and rarity of infant ALL is the major limitation for clinical trials, resulting in slow accrual over long time periods and limiting study power.
Resistance is also a major limitation for both Iressa and Tarceva.
However, the mechanical brittleness is the major limitation for their applications.
However, this represents a major limitation for many processing techniques of hydrogel materials.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com