Sentence examples for major limitation when from inspiring English sources

Hence, this presents a major limitation when attempting to develop antibodies against challenging target antigens.

As a result, these methods have slow temporal resolution which is a major limitation when investigating live-cell dynamics.

The small sample size in our study is a major limitation when screening for low frequency SNPs.

Microdialysis contains a major limitation when estimating data because only an approximation can be stated.

This is a major limitation when it comes to comparing studies and developing biomarkers.

This fact has to be considered as one major limitation when discussing trainees' early ADR values.

Major limitations when decreasing electrode size in dense arrays are increased noise level and low charge injection capability.

Nevertheless, low cell seeding efficiency and non-uniform distribution of cells remain major limitations when using such types of scaffold.

Both study designs had major limitations when addressing infection risk.

This finding suggests that factor analysis may have major limitations when applied to surveys that contain several discrete validated instruments that use different response patterns and group questions according to diagnosis or co-locate questions pertaining to each domain as part of a larger survey.

One of the major limitations occurs when local or regional sources of 137Cs contamination mask the pulse from global fallout, making temporal estimates of redistribution difficult or impossible.