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The major issue associated with horizontal subsurface flow constructed wetlands for wastewater treatment is clogging.
The lead compound was found to be roughly equipotent to morphine (ED50 3.13 ± 1.09 mg/kg) but devoid of the dangerous side-effect respiratory depression, a major issue associated with traditional opioid therapy.
A major issue associated with the deployment of such networks is represented by energy consumption: in general, the batteries of the sensors cannot be easily replaced and recharged, so containing the usage of energy by a rational design of the network and of the routing is crucial.
However, it is a costlier metal, and another major issue associated with it is the CO poisoning which degrades the operational stability of an FC [10].
A major issue associated with surgery for gastric SMTs is the difficulty in determining an appropriate dissection line, especially for small intraluminal tumors.
One major issue associated with the challenge of the world's increasing demand for energy is the electrification for approximately two billion people [1] in developing countries that do not currently have access to electricity.
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Three major issues associated with numerical simulations of complex free-surface flows, viz.
This paper in turn addresses two major issues associated with buildings.
One of the major issues associated with the implementation of direct-current distribution systems is the design of a proper protection scheme.
One of the major issues associated with structures located in the tsunami inundation zone is impact of massive objects carried by the tsunami flow.
Major issues associated with the use of automated sensor systems are the weight of financial investment, the lack of economic analysis and limited skills of the users to manage associated technologies.
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CEO of Professional Science Editing for Scientists @ prosciediting.com