The alternative splicing of vegf mRNA renders three major isoforms of 121, 165 and 189 amino-acids in humans.
The MCT isoforms 1 and 4 are the major isoforms of this transporter in skeletal and cardiac muscle.
NDPK-A, product of the nm23-H1 gene, is one of the two major isoforms of human nucleoside diphosphate kinase.
To determine whether differences in the production of any or all of the major VEGF-A isoforms are related to stage of progression, we compared message levels for the three major isoforms of VEGF in melanoma specimens from different stages of progression.
There are two major isoforms of WNK1: L-WNK1 and Ks-WNK1.
We show that there are two major isoforms of palladin in pancreatic tumors: 65 kDa and 85 90 kDa.
There are two major isoforms of WNK1, a kinase-active long isoform (L-WNK1) and a kinase-deficient kidney specific short isoform (Ks-WNK1).
To address the expression profile of the two major isoforms of p63, in the present study, we have utilized ΔN and TA specific antibodies.
We analyzed the N-linked glycosylation of the five major isoforms of A1AT and discovered, in addition to increased levels of core fucosylation, significant increases in outer arm fucosylation with the development of liver cancer.
The major isoforms of HLA-G present in serum are soluble HLA-G1 and HLA-G5 generated either by shedding or proteolytic cleavage of the membrane bound isoform or by secretion of a soluble isoform[6].
Immunohistochemistry with our PA3111 antibody [16], [43] (Figures 1B, C and 2), which recognizes all three major isoforms of dysbindin-1, revealed that this protein is neuronal, not glial.
