Your English writing platform
Discover LudwigSuggestions(1)
Exact(1)
Three major interlocked feedback loops constitute the plant circadian clock: the central loop, the morning loop, and the evening loop [ 3- 5].
Similar(59)
If we accept the hypothesis of GI as the "factor Y" in an interlocked feedback loop through light affecting TOC1 expression [33], we must conclude that CRY1a plays a major role in the input to the tomato circadian clock.
Identification of core clock components and their associated molecular interactions has established the basic network architecture of plant clocks, which consists of multiple interlocked feedback loops.
These results differ from the dynamical properties resulting from interlocked feedback loops systems in which a given variable is involved at the same time in both positive and negative feedbacks.
MAR combines the numerical sensitivity analysis with the CV analysis to identify the critical reactions in the interlocked feedback model.
In mammals, the circadian clock relies on interlocked feedback loops involving clock genes and their protein products.
The interlocked feedback is able to provide robustness to the circadian rhythm when the kinetic parameters are appropriately tuned.
MAR identifies the reactions critically responsible for determining the period and amplitude in the interlocked feedback model and suggests that the circadian clock intensively evolves or designs the kinetic parameters so that it creates a highly robust cycle.
In terms of engineering design concept, the circadian clock is suggested to not only evolve an interlocked feedback system but also intensively design kinetic parameters for further enhanced robustness.
In mammals, the circadian clock relies on interlocked feedback loops in which a heterodimer of transcription factors, CLOCK/BMAL1 (CLK/BM1), drives transcription of Period1-3 (Per1-3) and Cryptochrome1-2 (Cry1-2) genes through E-Box cis-elements.
Compared with the previous method that systematically analyzed two-dimensional parameter space in the per-time feedback model [10], MAR enables more precise analysis of more complex models, the interlocked feedback model that contains the per-tim and dclk-cyc loops.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com