Sentence examples for major inflammatory pathway from inspiring English sources

Another major inflammatory pathway in the mucosa is controlled by the release of IL-23.

Hereby, a major inflammatory pathway is the cleavage and activation of caspase-1, which is initiated upon the formation of large multiprotein signalling platforms, the so-called inflammasomes.

The underlying mechanisms may include epigenetic modulation of major inflammatory pathways, yet the details remain unclear.

IRAK-4 and IL-18, two major inflammatory pathways, seem to be involved in PMA triggered brain injury.

NF- κB and STAT3 represent major inflammatory pathways for pro-inflammatory cytokines and contribute to the chemoresistance of tumours (Aggarwal et al, 2009).

Evidence suggests that with substrate excess there are metabolically induced increased oxidative processes, increased reactive oxygen species, and increased storage challenges carrying consequences for ER stress signalling through the major inflammatory pathways.

60 Hence, JNK AP-1 and IKK–NFκB are the maJNK AP-1andatory pathways that dIKK NFκBnsulin signareng via a series of thenscriptional events and can be potentially majorated to inflammatorylin sensitivity and glucose homeostasis.

MAP3K14 induces NF-kappa-B signaling, a major inflammatory response pathway [ 35].

We examined whether VILI affects the activation of JNK1 and p38 MAPK, members of major inflammatory signaling pathways involved in lung injury.

For example, PPAR-γ has been shown to down-regulate the expression of inflammatory cytokines, inhibit major inflammatory signaling pathways [ 65], and direct immune cell differentiation towards anti-inflammatory phenotypes [ 66].

NF-κB is a nuclear protein that regulates transcription of many gene products that activate major pulmonary inflammatory pathways, including responses to O3 (Cho et al. 2007).