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These options have fairly major implications, and good quality genetic counselling is crucial to ensure that decisions are made based on the best quality information and true appreciation of the potential harms, as well as an understanding of the putative gains and risk reduction.
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"It's part of the biggest shakeup to the water industry since privatisation in 1989 and has major implications for companies and consumers alike".
The mechanism by which partial occupancy with an inhibitor can activate kinases may be wide-spread and carries major implications for design and therapeutic application of kinase inhibitors.
Both VILI and VIDD have major implications for morbidity and mortality.
Our findings have major implications for clinicians and healthcare institutions and add to the body of literature on the prevalence and impact of CDI.
If true, the idea would have major implications for blood and bone marrow donation, and for patients undergoing cancer treatments that destroy fertility.
Most patients with HCC, however, have two diseases – liver cirrhosis and HCC – and complex interactions between the two have major implications for prognosis and treatment choice 9.
Inter- and intra-tumoural heterogeneity have major implications for therapy and pose serious challenges for the rational design of effective treatment principles.
An armed conflict would have major implications at regional and international levels since Zimbabwe, Malawi and Zambia depend extensively on Mozambican ports.
Social learning has in fact major implications for roles and skills that will generate important educational and training needs at a general societal level (Ison et al. 2007).
As we are seeing in Canada and Australia, electoral politics can have major implications on climate and clean energy policy, both for good and bad.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com