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One of the major impediments of GDEPT is to target specifically the tumor cells with the suicide gene.
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Multidrug resistance (MDR), a phenotype of cross-resistance to multiple drugs with diverse chemical structures is the major impediment of successful application of chemotherapy [1].
The major impediment of the murine monoclonal antibody in clinical practice is that it may elicit human anti-murine antibody (HAMA) response in patients [4], [5], [6].
A major impediment of meta-coexpression analysis is the differences among experiments.
Chloroplast genetic engineering has a number of advantages over nuclear transformation; it not only increases transgene expression but also facilitates transgene containment, which is one of the major impediments for development of transgenic trees.
are highly susceptible to sylvatic plague (Yersinia pestis), and this disease is considered one of the major impediments to recovery of the endangered black-footed ferret (Jachowski and Lockhart 2009) as well as the threatened Utah prairie dog (C. parvidens; USFWS 2009).
Gene flow from transgenic plants to compatible wild relatives is one of the major impediments to the development of the culture of genetically engineered crop plants.
One of the major impediments to the modeling of breast cancer is our lack of data on its natural history.
In chlamydia research, the lack of effective adjuvants has indeed been one of the major impediments for the development of an effective vaccine.
The new algorithms overcome one of the major impediments to the application of profile HMMs in the transposon modeling problem: that of poor parameter estimation.
Counterintuitive as it may sound, one of the major impediments to the growth of women's wrestling at larger universities, some argue, is Title IX.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com