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The advertisement, disputed by the candidate, is part of a large-scale effort by two independent advocacy groups to turn a relatively low-profile pro-labor vote in Congress into a major impediment for Democrats as they seek to expand their Senate majority.
Multidrug resistance is a major impediment for the successful chemotherapy in breast cancer.
The inherent uncertainty of the wind is a major impediment for successful implementation of wind based power generation technology.
Shelby accepts, for the sake of argument, the idea that "suboptimal cultural traits" are the major impediment for many African-Americans seeking to escape poverty.
Catherine Ashton, the E.U. foreign policy chief, said earlier in the year, "The current arms embargo is a major impediment for developing strong E.U.-China cooperation.
The intrinsic properties of therapeutic proteins generally present a major impediment for transdermal delivery, including their relatively large molecule size and susceptibility to degradation.
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Major impediments for structural and biophysical studies of peptide self-assemblies include their insolubility and heterogeneous composition.
One of the major impediments for the transition to a hydrogen based energy system is the lack of satisfactory hydrogen storage alternatives.
The elitist processes of decision-making and a lack of a consistent urban policy and planning regimes are argued to be among major impediments for a more sustainable development of this city.
In chlamydia research, the lack of effective adjuvants has indeed been one of the major impediments for the development of an effective vaccine.
These recent breakthroughs undoubtedly lift major impediments for key players in drug development, in the study of transcription factors as potential molecular targets.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com