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"The reforms will not have a major impact in this parliament.
This alone would have a major impact in deterring overseas libel claims.
Gates said US aid had "a major impact" in improving agricultural productivity in the world's poorest nations.
In my general assessment of the Katine project, I am not seeing a major impact in the community.
The film's creators say simulating the workings of the heart accurately could have a major impact in medicine.
It is no secret that corporations have long had a major impact in the choice of weapons systems.
Lindeberg made his first major impact in fashion spearheading Italian denim brand's Diesel's celebrated ad campaigns of the 1990s.
The women's tour has been waiting for several years for the influx of Russian players to start having a major impact in Grand Slam events.
After a string of small roles, Gandolfini made a major impact in True Romance, the Quentin Tarantino-scripted thriller directed by the late Tony Scott.
A dynamic Swiss octogenarian named Marc Hodler is perhaps the only person to have made a major impact in three areas.
"We showed that this low-cost intervention can have a major impact in saving lives," said Dr. James S. Krinsley, director of critical care at the Stamford I.C.U.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com