A multiplex Primer-Extension Reaction (PER) assay, was specifically designed for the identification, of the major human pathogenic Vibrio species (V. cholerae, V. parahaemolyticus, V. vulnificus, V. mimicus, V. alginolyticus and V. fluvialis) in fishery products.
Cryptococcus neoformans is a major human pathogenic fungus that can cause meningoencephalitis in immunocompromised hosts.
This also argues against very recent acquisition from the related major human pathogenic streptococci, GAS, GBS, and S. pneumoniae as they average 3-to-7% lower in G+C composition than S. zooepidemicus.
In comparison to the major human pathogenic streptococcal species, the genome is modestly larger than genomes of group A Streptococcus pyogenes (GAS) (ave. 1.88 Mbp, n = 12 strains), and smaller than those of group B Streptococcus agalactiae (GBS) (ave. 2.17 Mbp, n = 3 strains) or Streptococcus pneumoniae (ave. 2.12 Mbp, n = 4 strains).
Overall, 4% of the dog sera we tested contained neutralizing EVEV antibodies, a rate similar to the seroprevalence for the major human pathogenic arboviruses (EVEV, EEEV, Saint Louis encephalitis virus, Western equine encephalitis virus) in Florida detected in >2,500 sera from wildlife in 38 of the state's 67 counties from 1965 to 1974 (24 ).
In this study we have successfully used the publicly available genome sequence resources available for Campylobacter to study the distribution of CRISPR-Cas in this important foodborne pathogen, and show a striking difference in CRISPR-Cas distribution between the two major human pathogenic species C. jejuni and C. coli, and within C. coli a marked difference between agricultural isolates.
Of the paramyxoviridae, respiratory syncytial virus (RSV), measles virus (MeV), mumps virus (MuV), human parainfluenzaviruses (HPIV) and the recently emerged, highly pathogenic zoonotic henipaviruses constitute major human pathogens [1].
Campylobacter jejuni, Haemophilus influenzae, Helicobacter pylori, Mycobacterium tuberculosis, the pathogenic Neisseria, Streptococcus pneumoniae, Streptococcus pyogenes and Staphylococcus aureus are major human pathogens causing detrimental morbidity and mortality at a global scale.
This pathogenic agent is responsible for a wide spectrum of diseases, which includes life-threatening conditions like pneumonia or endocarditis [ 42], and emerges as a major human pathogen due to methicillin-resistant S. aureus (MRSA) strains.
Often healthy pigs are asymptomatic carriers of Y. enterocolitica; and they are a major reservoir for human pathogenic strains [ 3, 5, 6].
However, identifying the gp60 gene of the major emerging human-pathogenic species, C. ubiquitum, has been challenging (24 ).
