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Schistosomiasis (bilharziasis) is a major human disease caused by three species of the genus Schistosoma, known collectively as blood flukes.
Cellular pathology is observed in every major human disease and relies on the ability of histology to detect cellular change in any cell type due to unbiased pan-cellular staining, even in optically opaque tissues.
Polymerase-γ (POLG) is a major human disease gene and may account for up to 25% of all mitochondrial diseases in the UK and in Italy.
The METAcancer project has been the first large-scale effort to combine the three major metabolomic technology platforms for analyzing a major human disease.
It is becoming clear that POLG is a major human disease gene, possibly accounting for up to 25% of all patients with mitochondrial diseases in the UK and in Italy (Chinnery and Zeviani, 2008).
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Protists have been used as model cells in laboratory research, some of which is directed against major human diseases.
Many major human diseases are produced by microorganisms conveyed by insects, which serve as vectors of pathogens.
However, we still lack efficient vaccines against major human diseases such as malaria or tuberculosis.
The application of RNAi therapeutics is promising in combating several major human diseases including malignant tumors.
Sugar polymers, called glycans, are universal in living organisms, and play a role in virtually all major human diseases.
Ch6 is functionally associated with more than 120 major human diseases, many with high population prevalence, devastating clinical impact and profound societal consequences.
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substantial human disease
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major economic disease
major human trial
major human development
major underlying disease
major human developmental
major blinding disease
major human toxicant
major human fungal
major human respiratory
major human malnutrition
major human cancer
major human ARDs
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