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About 30% of the mutations are found in six major "hot spot" codons located in its DNA binding core domain.
"It's tipped as a major hot spot in the design community, more foreigners live here than ever before, and there's new restaurants popping up everywhere".
The major hot spot island groups such as the Hawaiian (which has been active over the past 30 million years), Galapagos, and Society (which were active during the Miocene) islands are volcanoes that rose from the seafloor.
We discovered a major hot spot in Gaza.
In apple, Md-PG1, a key gene belonging to the polygalacturonase gene family, was mapped on chromosome 10 and co-localized within the statistical interval of a major hot spot QTL associated to several fruit texture sub-phenotypes.
We had problems gaining access to at least one major hot spot in Israel 600 children in a school near a smelter battery factory in the north of the country (Kfar Vradim), who, at the time of this writing, reportedly had been exposed to lead in previous years.
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The best model is employed to investigate major hot spots identified where wind farming is feasible in Mauritius with due consideration to land use and topographical requirements.
The two major hot spots are the bohemian Ä, an eclectic scene that offers occasional live music, art installations and a storytelling night, and Tier, a more upscale hangout across the street.
The distribution of mutations observed in NBS patients was largely similar to that found in normal controls, with major hot spots of mutation at previously described RGYW/WRYC motifs (AGCT at position 72 and 129 and AGCA at position 150; Fig. 1B).
"There are major hot spots at all of the industrialized nations of the world.
Some of these areas were shown to represent major hot spots of genetic diversity, e.g. in gallwasps [ 105].
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