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If you have none, it's a major handicap to overcome.
And if prime location is everything, his venture had a major handicap.
"It is a major handicap that prevents us from the proper monitoring of food insecurity".
In years past, such damage has proved a major handicap in November.
The world shortage of fertilizer is a major handicap to all developing countries in the medium term.
As this generation of entrepreneurs tries to deploy the Internet, a major handicap is the absence of management expertise.
Similar(11)
Thailand's inability to take criticism, and its greatly flawed justice system, are major handicaps to its progress".
Prescott has always enjoyed the challenge of laying out a horse to win one of the Flat's major handicaps.
Has been noted as jumping to the right in the past and made jumping errors and was well beaten when tried in major handicaps at left-handed tracks.
Hold-up tactics and jumping errors get in his way, with the result that he has finished strongly but too late in several major handicaps at Cheltenham.
He comes from the William Haggas stable that does well in major handicaps and Haggas could do with a change of luck after two runners-up yesterday.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com