Sentence examples for major gist from inspiring English sources

"You lose a little bit of the clarity and the graphics don't stack up as well as something like a PC or a console, but you do get most of the major gist of the experience".

The UK GEM Registry has currently been implemented or is in the process of being implemented at 10 major GIST centres in the UK (including those represented by the authors).

Stirling ordered all of his troops, except a contingent of Maryland troops under the command of Major Mordecai Gist, to cross the creek.

Thus, KIT activation plays a major role in GIST oncogenesis.

KIT plays a major role in GIST oncogenesis.

These mutations also play a major role in GIST oncogenesis.

Thus, although these two important studies have been published, major questions about GIST biology remain open.

ADAM17, which has been shown to mediate L1 cleavage [ 15] has also been identified as a major sheddase in GIST [ 37].

In conclusion, although KIT gain-of-function mutations play a major role in GIST oncogenesis, we show that KIT activation in these tumours is unrelated to the presence of these mutations, and may result from an autocrine/paracrine mechanism.

Although the tyrosine kinase inhibitor imatinib mesylate considerably improved the outcome of patients, imatinib resistance still remains a major therapeutic challenge in GIST therapy.

Patients were stratified to three major disease groups; non-GIST patients with prior chemotherapy evaluated by WHO criteria, non-GIST patients without prior chemotherapy evaluated by WHO criteria and RECIST criteria, and GIST patients without prior therapy evaluated by WHO criteria.