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Six major genotypes and more than 50 minor subtypes have be distinguished.
HCV is classified in the family Flaviviridae genus hepacivirus, with six major genotypes and multiple serotypes.
HCV is classified in six major genotypes and more than 70 subtypes [24], [25].
Variations of the HCV genome have led to its classification into six major genotypes and a large number of subtypes.
Hepatitis C virus (HCV) has six major genotypes, and patients infected with genotype 1 respond less well to interferon-based therapy than other genotypes.
HCV is classified into six major genotypes and many subtypes, varying in geographical distribution, transmission route and treatment response [1], [8], [9].
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The SAFV type 3 (SAFV-3) is thought to be the major genotype and is detected relatively frequently in children with acute gastroenteritis and respiratory illness.
We set x j i =0 if the j-th SNP from the i-th sample is a major genotype and x j i =1 if it is a minor genotype.
Formalin-fixed, paraffin-embedded colonic biopsy samples from six VEO-IBD patients (three with major genotype and three with risk genotype) were obtained from the Department of Pathology at the Hospital for Sick Children with approval of the institutional review ethics board for IBD genetic studies at the Hospital for Sick Children.
Briefly, the breast cancer incidence rate λ(t) was assumed to be based on the Cox model (Cox and Oakes, 1984), λ(t)=λ0 t)exp(G+ P). λ0 t) is the baseline incidence rate, G depends on the major genotype and P is the polygenic component, which is assumed to be normally distributed with zero mean and variance.
Hepatitis C virus is divided into six major genotypes (1 6) and several closely related subtypes (for example, 1a or 1b) that differ approximately by 30% in nucleotide and amino acid sequences (Simmonds et al. 2005).
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